Leveraging our cutting-edge technology based on protein dynamics, Nutshell is fostering a new
era of drug discovery…
Our AlloStar allosteric drug discovery platform, composed of a
powerful and well-integrated set of computational modules and experimental tools based on our
proprietary AI algorithm and deep know-how derived from biochemistry and biophysics, possesses
the unique capability to discover a host of drug entities including various types of protein activators,
subtype/mutation selective small molecules, regulatory molecules of protein-protein interaction (PPI)
and stabilizer of intrinsically disordered proteins (IDPs), thus opening up an unprecedented new horizon
for small molecule innovation.


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Sub-type selective allosteric inhibitor
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Mutants selective allosteric inhibitor
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Enzyme allosteric activator
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Protein-protein interaction modulator
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Disordered protein stabilize modulator
Current Pipeline
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Project
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Indication
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MoA
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Discovery
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Hit-to-Lead
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PCC
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Clinical I-III
Contact Us
AI Lab
Room 6108, No.338 Jialilue Rd. Pudong district, Shanghai, China
+86 21 51061769
contact@allonutshell.com;BD@allonutshell.com
Drug Discovery Lab
Building E, No.1976 Middle Gaoke Rd. Pudong district, Shanghai, China
+86 21 51061769
contact@allonutshell.com;BD@allonutshell.com
